Research has shown that engineered tissues can be successfully constructed through the recreation of biologically active extracellular 3D micro-environments in which the tissue can be developed.
Peptidic scaffolds are designed for regenerative medicine applications such as the regeneration of damaged tissues. Nanomed3D peptides spontaneously assemble to form hydrogels, which resemble the nanostructure of the extracellular matrix found in living tissues
Facing the Challenges of Regenerative Medicine
Living cells interact with each other and with their surroundings in complex and unique ways. The biological world is three dimensional and yet since its beginning, biology has been carried out on the flat surfaces of test tubes, slides and petri dishes. The growing field of regenerative medicine requires controlled, predictable and scalable environments for cell culture.
Cells which have been outside the body may not graft, survive or differentiate when re-implanted
Whenever a consistent loss of tissue occurs a physical support, a scaffold, is needed to favor transplanted cell engraftment and trigger tissue regeneration
Some types of cells do not grow outside of the body unless they are embedded in biomimetic nano- and microstructures
Cells require three-dimensional micro-environments with tuned mechanical properties to thrive, differentiate and form tissues
Materials used to handle and treat cells which are then re-implanted must be biocompatible, sterile, tunable and 100% controlled
Each type of cell has its own precise 3D microenvironment for optimum cellular homeostasis and function
