Selected Publications

2020 Marchini A, Favoino C, Gelain F “Multi-functionalized self-assembling peptides as reproducible 3D cell culture systems enabling differentiation and survival of various human neural stem cell lines.” Frontiers in Neuroscience 14: art.413 doi: 10.3389/fnins.2020.00413

2020 Fontana F, Gelain F “Probing mechanical properties and failure mechanisms of fibrils of self-assembling peptides” Nanoscale Advances 2: 190-198. doi: 10.1039/c9na00621d

2019 Jekhmane S, Prachar M, Pugliese R, Fontana F, Medeiros-Silva J, Gelain F*, Weingarth M* “Design parameters of tissue engineering scaffolds at atomic scale” Angewandte Chemie Int. Ed. 58: 2-11. doi: 10.1002/anie.201907880

2019  Marchini A, Raspa A, Pugliese R, Abd El Malek M, Pastori V, Lecchi M, Vescovi AL, Gelain F “Multi-functionalized hydrogels foster hNSC maturation in 3D cultures and neural regeneration in spinal cord injuries” Proc Natl Acad Sci U S A. 116(15):7483-7492. doi: 10.1073/pnas.1818392116

2019  Pugliese R, Maleki M, Zuckermann RN, Gelain F “Self-assembling peptides cross-linked with Genipin: resilient hydrogels and self-standing electrospun scaffolds for tissue engineering applications” Biomaterials Science 7, 76-91 doi: 10.1039/C8BM00825F.

2018  Saracino G, Fontana F, Jekhmane S, Silva JM, Weingarth M, Gelain F “Elucidating self-assembling peptide aggregation via Morphoscanner: a new tool for protein-peptide structural characterization” Advanced Science doi: 10.1002/advs.201800471.

2018  Raspa A, Bolla E, Cuscona C, Gelain F “Feasible stabilization of chondroitinase abc enables reduced astrogliosis in a chronic model of spinal cord injury” CNS Neuroscience & Therapeutics doi: 10.1111/cns.12984.

2018  Pugliese R, Marchini A, Saracino G, Gelain F “Functionalization of self-assembling peptides for neural tissue engineering” Self-Assembling Biomaterials: Molecular Design, Characterization and Application in Biology and Medicine. Elsevier, Amsterdam, NL: 475-493. Book Chapter.

2017  Pugliese R, Fontana F, Marchini A, Gelain F “Branched peptides integrate into self-assembled nanostructures and enhance biomechanics of peptidic hydrogels” Acta Biomaterialia. 66: 258-271 doi: 10.1016/j.actbio.2017.11.026.

2017  Pugliese R, Marchini A, Saracino GA, Zuckermann RN, Gelain F “Cross-linked self-assembling peptide scaffolds” Nano Research. 11(1): 586-602. doi: 10.1007/s12274-017-1834-6.

2017  Maleki M, Natalello A, Pugliese R, Gelain F “Fabrication of nanofibrous electrospun scaffolds from a heterogeneous library of co- and self-assembling peptides” Acta Biomaterialia. 51: 268-278. doi: 10.1016/j.actbio.2017.01.038.

2017  Pugliese R and Gelain F “Peptidic biomaterials: from self-assembling to regenerative medicine” Trends in Biotechnology. 35(2): 145-158. doi: 10.1016/j.tibtech.2016.09.004.

2016  Raspa A, Marchini A, Vasita R, Maleki M, Pugliese R, Mauri M, Gelain F “A biocompatibility study of new nanofibrous scaffolds for nervous regeneration” Nanoscale 8(1): 253-265. doi: 10.1039/c5nr03698d.

2016  Raspa A, Pugliese R, Maleki M, Gelain F “Recent therapeutic approaches for spinal cord injury” Biotechnology & Bioengineering 113(2): 253-259. doi: 10.1002/bit.25689.

2014  Bradshaw M, Ho D, Fear MW, Gelain F, Wood FM, Iyer KS “Designer self-assembling hydrogel scaffolds can impact skin cell proliferation and migration.”  Scientific Reports 4:6903 doi: 10.1038/srep06903.

2014  Raspa A, Saracino G, Pugliese R, Silva D, Cigognini D, Vescovi A, Gelain F “Complementary Co-Assembling Peptides: from in silico studies to in vivo application.” Advanced Functional Materials 40(24): 6317-6328. doi: 10.1002/adfm.201400956.

2014 Cigognini D, Silva D, Paloppi S, Gelain F “Evaluation of mechanical properties and therapeutic effect of injectable self-assembling hydrogels for spinal cord injury.” Journal of Biomedical Nanotechnology 10(2): 309-323. doi: 10.1166/jbn.2014.1759.

2013  Saracino G and Gelain F “Modeling and analysis of early aggregation events of BMHP1-derived self-assembling peptides.” Journal of Biomolecular Structure & Dynamics 32(5): 759-775. doi: 10.1080/07391102.2013.790848.

2013  Caprini A, Silva D, Zanoni I, Cunha C, Volontè C, Vescovi A, Gelain F “A Novel Bioactive Peptide: Assessing its Activity Over Murine Neural Stem Cells and its Potential for Neural Tissue Engineering.”  New Biotechnology 30(5): 552-562. doi: 10.1016/j.nbt.2013.03.005.

2013  Cunha C, Panseri S, Gelain F. “Engineering of a 3D Nanostructured Scaffold Made of Functionalized Self-Assembling Peptides and Encapsulated Neural Stem Cells.” Methods in Molecular Biology. 2013 Clifton, NJ: Book Chapter doi: 10.1007/7651_2012_2.

2013  Vasita R, Gelain F. “Core-sheath Fibres for Regenerative Medicine” Nanomaterials in Drug Delivery, Imaging, and Tissue Engineering. Wiley-Scrivener Publishing, Beverly: 493-533. Book Chapter.

2013  Silva D, Natalello A, Sanii B, Vasita R, Saracino GAA, Zuckermann RN, Doglia SM, Gelain F “Synthesis and Characterization of Designed BMHP1-Derived Self-Assembling Peptides for tissue engineering applications.” Nanoscale 5(2):704-718. doi: 10.1039/c2nr32656f.

2013  Saracino GAA, Cigognini D, Silva D, Caprini A, Gelain F “Nanomaterials design and tests for neural tissue engineering.” Chemical Society Reviews 42(1):225-262.

2012  Gelain F, Cigognini D, Caprini A, Silva D, Colleoni B, Donegá B, Antonini S, Cohen BE, Vescovi A. “New Bioactive Motifs and Their Use in Functionalized Self-Assembling Peptides for NSC Differentiation and Neural Tissue Engineering” Nanoscale 4(9):2946-2957.

2012  Zhang S, Yokoi H, Gelain F, Horii A “Designer Self-Assembling Peptide Nanofiber Scaffolds” Nanotechnology for Biology and Medicine: At the Building Block Level, Springer Science/Business Media Press, New York City: 123-147. Book Chapter

2011  Cigognini D, Satta A, Colleoni B, Silva D, Donega’ M, Antonini S, Gelain F “Evaluation of Early and Late Effects into the Acute Spinal Cord Injury of an Injectable Functionalized Self-assembling Scaffold”. PLoS ONE 6(5):1-15.

2011  Cunha C, Panseri S, Villa O, Silva D, Gelain F “3D culture of adult mouse neural stem cells within different functionalized self-assembling peptide scaffolds” International Journal of Nanomedicine 6: 943-955.

2011  Gelain F, Silva D, Caprini A, Villa O, Taraballi F, Natalello A, Nam KT, Doglia SM, Vescovi A “BMHP1-derived self-assembling peptides: hierarchically assembled structures with self-healing propensity and potential for tissue engineering applications.” ACS Nano 5(3):1845-59.

2011  Gelain F, Panseri S, Antonini S, Cunha C, Donega M, Lowery J, Taraballi F, Cerri G, Montagna M, Baldissera F, Vescovi A “Transplantation of nanostructured composite scaffolds neuro-prosthetics results in tissue reconstruction, axonal regeneration and neurological recovery in the chronically injured rat spinal cord.” ACS Nano 5(1): 227-236.

2010  Gelain F, Unsworth L, Zhang S “Slow and sustained release of active cytokines from self-assembling peptide scaffolds” Journal of Controlled Release 145(3):231-239.

2010  Taraballi F, Natalello A, Campione M, Doglia SM, Paleari A, Gelain F “Glycine-spacers influence over functional motif exposure and self-assembling propensity of functionalized peptides” Frontiers in Neuroengineering 3:1-9.

2009  Antonini S, Vescovi A, Gelain F “Stem cells and biomaterials: the tissue engineering approach” Stem Cells & Regenerative Medicine, Springer/Humana Press, New York City. Book Chapter

2009  Gelain F, Wang X, Horii A, Hucknall A, Koutsopoulos S, Zhang S “Designer self-assembling peptides scaffolds for 3-dimensional tissue cell cultures” Methods in Bioengineering, Artech House Press, Boston: 59-81. Book Chapter

2009  Lowery J, Panseri S, Cunha C, Gelain F “Electrospinning for Tissue Engineering Applications” Electrospun Nanofibers Research: Recent Developments, NOVA Science Publishers, Hauppauge.: 1-18. Book Chapter

2009  Taraballi F, Campione M, Vescovi AL, Sassella A, Paleari A, Whang W, Gelain F “Effect of Functionalization on the Self-Assembling Propensity of β-Sheet Forming Peptides.” Soft Matter 5(3):660-668.

2008  Gelain F “Novel opportunities and challenges offered by nanobiomaterials in tissue engineering” International Journal of Nanomedicine 3(4):415-424.

2008  Panseri S, Cunha C, Lowery J, Del Carro U, Taraballi F, Amadio S, Vescovi A, Gelain F “Electrospun micro- and nanofiber tubes for functional nervous regeneration in sciatic nerve transections” BMC biotechnology 8(39) doi:10.1186/1472-6750-8-39.

2007  Gelain F, Horii A, Zhang S “Designer active 3D self-assembling peptide scaffolds for regenerative medicine.” Macromolecular Biosciences 7(5):544-551.

2007  Gelain F, Lomander A, Vescovi AL, Zhang S “Systematic studies of a self-assembling peptide nanofiber scaffold with other scaffolds” Journal of  Nanoscience and Nanotechnology 7(2):424-434.

2007  Horii A, Wang X, Gelain F, Zhang S “Biological designer self-assembling peptide nanofiber   scaffolds significantly enhance osteoblast proliferation, differentiation and 3-D migration.” PLoS ONE 2(2): e190.doi:10.1371.

2006  Gelain F, Bottai D, Vescovi AL, Zhang S “Designer self-assembling peptide nanofiber scaffolds for 3-D culture of adult mouse neural stem cells.” PLoS ONE 1(1): e119.doi:10.1371.

2005  Zhang S, Gelain F, Zhao X “Designer self-assembling peptide nanofiber scaffolds for 3D tissue cell cultures.” Seminars in Cancer Biology 15(5): 413-420.